The trailhead (where you park your vehicle and begin your 8 mile hike to the Village of Supai) is called Hualapai Hilltop and is located at the end of Indian Road 18, 60 miles from the turnoff from Route 66 (which is 7 miles east of Peach Springs, Arizona). Indian Road 18 is paved - but is open range with many animals crossing the road, so please drive extra carefully. Plan for at least 1.5 to 2 hours for this section of road.
The closest gas stations are nearly 70 miles from the trailhead (in Peach Springs on the way to/from Las Vegas, and at Grand Canyon Caverns on the way to/from Phoenix) and may not be open, so please be sure to have enough fuel in your vehicle to cover at least 200 miles of driving before starting down Indian Road 18. The next closest gas stations are in Kingman (to/from Las Vegas) and Seligman and Ash Fork (to/from Phoenix).
There is plenty of parking for all visitors but do not park in areas that say ""No Parking"" and do not park in the parking area by the helipad (that parking area is only for members of the Havasupai Tribe). While you can park next to the road, do not park on the road. If you ignore these warnings, expect your vehicle to be towed away. Parking is very tight for RV's - you may have to park some distance away from the trailhead along the side of the road - and it may be difficult to be able to turn around on the way out.
There are currently no public transportation options to/from the trailhead.